Investigating a New Treatment Plan for DKA

Investigational
ENROLLING

Overview

Has your dog been diagnosed with diabetic ketoacidosis? Help us find a new treatment

Complete the registration form to find out if your pet qualifies to be in our clinical trial.

Diabetic Ketoacidosis (DKA) is a serious complication of diabetes that occurs when the body produces high levels of ketones which causes the blood to be more acid than is normal. This can be triggered by infection or other illness. It can be life threatening and treatment requires hospitalization with IV (intravenous) fluids and insulin therapy. The usual treatment of DKA is to give regular insulin intravenously based on a sliding scale relative to their blood glucose level in addition to other standard supportive care therapies. We would like to investigate if a different (novel) scale for insulin therapy is more effective. This novel administration protocol more closely mimics the insulin regimen in human medicine. Our goal is to find a protocol that results in faster resolution of the DKA state which would result in shorter hospitalization times and lower costs to owners.

Compensation

Credit to your bill
A $516 credit will be applied to your bill upon allowing us to send a copy of the itemized bill to the sponsor.

Compensation

Hospital discount
You will receive 10% off your hospitalization costs for the study visit.

Location

Cornell

ITHACA, NY

Location

Cornell University Hospital for Animals (CUHA)

930 Campus Rd,

Ithaca, NY 14853

Study Team

Carol Frederick
Carol FrederickClinical Trials Coordinator

Carol graduated from SUNY Delhi in 1994 and became an LVT. She spent 2 years in private practice, then moved to the emergency and critical care department at Cornell University Hospital for Animals. She obtained her technician specialty in ECC in 2007. After 21 years in ECC she moved to clinical trials, and now is the lead trials coordinator at Cornell.

Apply today if...

Any dog diagnosed with DKA
Eligibility: Most dogs seen at the Cornell University Hospital for Animals who are diagnosed with DKA will be eligible.

Diabetic KetoAcidosis

Diabetic ketoacidosis is a medical emergency that occurs when there is not enough insulin in the body to control blood sugar (glucose) levels.  Insulin may also be prevented from working normally due to other hormones released as a result of certain diseases. The body cannot use glucose properly without insulin, so blood glucose levels get very high, and the body creates ketone bodies from fat as an emergency fuel source. While fine in an emergency, if glucose regulation is not restored, ketone levels increase resulting in a shift in the body's acid/base balance. The body becomes more acidic (acidosis), and it can't maintain appropriate fluid balance. The electrolyte (mineral) balance becomes disrupted which can lead to abnormal heart rhythms and abnormal muscle function. If left untreated, diabetic ketoacidosis is fatal.

About Diabetes

Diabetic ketoacidosis is a medical emergency that occurs when there is not enough insulin in the body to control blood sugar (glucose) levels.  Insulin may also be prevented from working normally due to other hormones released as a result of certain diseases. The body cannot use glucose properly without insulin, so blood glucose levels get very high, and the body creates ketone bodies from fat as an emergency fuel source. While fine in an emergency, if glucose regulation is not restored, ketone levels increase resulting in a shift in the body's acid/base balance. The body becomes more acidic (acidosis), and it can't maintain appropriate fluid balance. The electrolyte (mineral) balance becomes disrupted which can lead to abnormal heart rhythms and abnormal muscle function. If left untreated, diabetic ketoacidosis is fatal.